Targeting trafficking in drug development
tarafından
 
Tao, Ya-Xiong. editor.

Başlık
Targeting trafficking in drug development

Yazar
Tao, Ya-Xiong. editor.

ISBN
9783030089276

Basım Bilgisi
1st ed. 2018.

Fiziksel Tanımlama
vii, 425 pages : 57 illustrations ; 24 cm.

Seri
Handbook of Experimental Pharmacology ; 0171-2004. 245.

İçerik
1. Intracellular trafficking of gonadotropin receptors in health and disease -- 2. Investigating internalization and intracellular trafficking of GPCRs -- 3. Pharmacological chaperones as potential therapeutic strategies for misfolded mutant vasopressin receptors -- 4. Targeting of disordered proteins by small molecules in neurodegenerative diseases -- 5. Pharmacoperones for misfolded gonadotropin receptors -- 6. Pharmacological chaperones: Beyond conformational disorders -- 7. Natural (and unnatural) small molecules as pharmacological chaperones and inhibitors in cancer -- 8. Heritable skeletal disorders arising from defects in processing and transport of Type I procollagen from the ER: perspectives on possible therapeutic approaches -- 9. Conserved oligomeric Golgi and neuronal vesicular trafficking -- 10. SLC6 transporter folding diseases and pharmacochaperoning -- 11. The molecular physiopathogenesis of islet amyloidosis -- 12. Folding defects leading to primary hyperoxaluria -- 13. Potential pharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.

Özet
Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.

Konu Başlığı
Cell biology.
 
Hücre Biyolojisi.
 
Pharmacology.
 
Farmakoloji.

Yazar Ek Girişi
Tao, Ya-Xiong.
 
Ulloa-Aguirre, Alfredo.


LibraryMateryal TürüDemirbaşYer NumarasıDurumu / Lokasyon / İade Tarihi
Ekonomi KütüphanesiKitapEKOBKN0012479615 TAR 2018Eskişehir Yolu Yerleşkesi Genel Koleksiyon