Drugs desing and analysis için kapak resmi
Başlık:
Drugs desing and analysis
Yazar:
Lehman, Sam, editor.
ISBN:
9781632428325
Fiziksel Tanımlama:
vii, 234 pages ; 27 cm.
İçerik:
Chapter 1 Preparation and Characterization of Nanoatimpennion of Aprepitant by -- Chapter 2 Process, rhysicochemical Characteriztionn ti-Vitro Assessment ofAlbendazole microcrystals -- Chapter 3 IS-optimal Design for Preparation and Optimization of Fast Dissolving Bosentan Nanosuspension -- Chapter 4 Formulation and Physicochemical Characterization of Lycopene-Loaded Solid Lipid Nanoparticles -- Chapter 5 Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation -- Chapter 6 Development of Floating-Mucoadhesive Microsphere for Site Specific Release of Metronidazole -- Chapter 7 Assay of Desmopressin Acetate in Nasal Spray: Development of Validated Pre Column HPLC-Fluorescence Method -- Chapter 8 A Simple, Fast, Low Cost, HPLC/UV Validated Method for Determination of Flutamide: Application to Protein Binding Studies -- Chapter 9 Determining Abuse Deterrence Performance of Poly (ethylene oxide) using a Factorial Design -- Chapter 10 Prediction of Optimum Combination of Eudragit RS/Eudragit Rt./Ethyl Cellulose Polymeric Free Films Based on Experimental Design for using as a Coating System for Sustained Release Theophylline Pellets -- Chapter 11 Design and Conatructlon of Chimeric VP8-S2 Antigen for Bovine Rotavirus and Bovine Coronavirus -- Chapter 12 Novel Pentablock Copolymers as Thermosensitive Self-Assembling Micelles for Ocular Drug Delivery -- Chapter 13 Cloning and Expression of Recombinant Human Endostatin In Periplasm of Escherichia coli Expression System -- Chapter 14 Cord Blood Mononuclear Cells have a Potential to Produce NK Cells using IL2Rg Cytokines -- Chapter 15 Alteration in Inflammation-related miR-146a Expression in NF-KB Signaling Pathway in Diabetic Rat Hippocampus -- Chapter 16 Investigation of DNA-damage and Chromosomal Aberrations in Blood Cells under the Influence of New Silver-based Antiviral Complex -- Chapter 17 The Challenges of Recombinant Endostatin in Clinical Application: FOCus on the Different Expression Systems and Molecular Bioengineering -- Chapter 18 Formulation and Optimization of Oral Mucoadhesive Patches of Myrtus Communis by box Behnken Desing -- Chapter 19 Effect of Solubilizers on the Androgenic Activity of Basella Alba L (Basellaceae) in Adult Male Rats -- Chapter 20 Characterizing the Hot Spots Involved in RON-MSPIi Complex Formation using in Sillco Alanine Scanning Mutagenesis and Molecular Dynamics Simulation -- Chapter 21 The Different Mechanisms of Cancer Drug Resistance --Chapter 22 Thermal Stability and Kinetic Study of Fluvoxamine Stability in Binary Samples with Lactose-- Chapter 23 Pantoprazole Sodium Loaded Microballoons for the Systemic Approach: In Vitro and In Vivo Evaluation -- Chapter 24 Preparation and Microstructural Characterization of Griseofulvin Microemulsions Using Different Experimental Methods -- Chapter 25 Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models -- Chapter 26 Preparation, Optimization and Activity Evaluation of PLGA/Streptokinase Nanoparticles using Electrospray -- Chapter 27 Phospholipid Complex Technique for Superior Bioavailability of Phytoconstituents -- Chapter 28 The Utilization of RNA Silencing Technology to Mitigate the Voriconazole Resistance of Aspergillus Flavus; Lipofectamine-Based Delivery -- Permissions List of Contributors Index.
Özet:
The process of inventing and finding new medications on the basis of the knowledge of a biological target is called drug design. The chemical substances which activate or inhibit the functions of a biomolecule, and consequently result in therapeutic benefits to the patients are called drugs. They are usually obtained through extraction from several medicinal plants or by organic synthesis. Drug design is a process involving the design of such molecules which are similar in the shape and charge to the biomolecular target with which they interact, in order to bind to it. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of drug design and analysis. Different approaches, evaluations, methodologies and advanced studies on drug design and analysis have been included in it. The extensive content of this book provides the readers with a thorough understanding of the subject.
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Kitap EKOBKN0012516 615.19 DRU 2019
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