Targeting trafficking in drug development
tarafından
Tao, Ya-Xiong. editor.
Başlık
:
Targeting trafficking in drug development
Yazar
:
Tao, Ya-Xiong. editor.
ISBN
:
9783030089276
Basım Bilgisi
:
1st ed. 2018.
Fiziksel Tanımlama
:
vii, 425 pages : 57 illustrations ; 24 cm.
Seri
:
Handbook of Experimental Pharmacology ; 0171-2004. 245.
İçerik
:
1. Intracellular trafficking of gonadotropin receptors in health and disease -- 2. Investigating internalization and intracellular trafficking of GPCRs -- 3. Pharmacological chaperones as potential therapeutic strategies for misfolded mutant vasopressin receptors -- 4. Targeting of disordered proteins by small molecules in neurodegenerative diseases -- 5. Pharmacoperones for misfolded gonadotropin receptors -- 6. Pharmacological chaperones: Beyond conformational disorders -- 7. Natural (and unnatural) small molecules as pharmacological chaperones and inhibitors in cancer -- 8. Heritable skeletal disorders arising from defects in processing and transport of Type I procollagen from the ER: perspectives on possible therapeutic approaches -- 9. Conserved oligomeric Golgi and neuronal vesicular trafficking -- 10. SLC6 transporter folding diseases and pharmacochaperoning -- 11. The molecular physiopathogenesis of islet amyloidosis -- 12. Folding defects leading to primary hyperoxaluria -- 13. Potential pharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.
Özet
:
Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.
Konu Başlığı
:
Cell biology.
Hücre Biyolojisi.
Pharmacology.
Farmakoloji.
Yazar Ek Girişi
:
Tao, Ya-Xiong.
Ulloa-Aguirre, Alfredo.
Library | Materyal Türü | Demirbaş | Yer Numarası | Durumu / Lokasyon / İade Tarihi |
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Ekonomi Kütüphanesi | Kitap | EKOBKN0012479 | 615 TAR 2018 | Eskişehir Yolu Yerleşkesi Genel Koleksiyon |